KANSAS CITY, Mo. -- Jeremy Guthrie pitched his first career shutout, continuing his remarkable dominance against the White Sox while setting a Royals record with his 17th straight start without a loss, and Lorenzo Cain drove in two runs with a triple in the first inning on Saturday night, leading Kansas City to a 2-0 victory at Kauffman Stadium.
The Sox had four hits against Guthrie, a single by Paul Konerko in the second, a double by Konerko in the fourth, and singles by Tyler Flowers and Alejandro De Aza in the eighth. Guthrie has been sensational against the Sox, allowing two earned runs in 44 2/3 innings since he joined the Royals.
The Sox' best chance to score might have been on Konerko's two-out double to right-center with Adam Dunn (walk) on first. Dunn rounded third with the intent of scoring, but third-base coach Joe McEwing held him up on what could have been a close play at home. Conor Gillaspie then struck out to end the inning.
Flowers' and De Aza's singles put runners on first and second with two outs in the eighth, but Guthrie got struggling Jeff Keppinger (.186) to hit into a force out to shortstop Alcides Escobar. Keppinger was 0-for-4.
Dyland Axelrod (0-2) made his fourth consecutive quality start, scattering eight hits and allowing two runs over 7 2/3 innings. Axelrod threw a season-high 113 pitches and went into the eighth inning for the first time. Axelrod hit Billy Butler and Mike Moustakas with pitches -- both in the first inning -- walked one and did not strike out a batter, getting 18 fly outs.
The Sox committed their 19th and 20th errors on consecutive plays in the seventh inning, both after two outs, but the miscues did not cost them any runs. Shortstop Alexei Ramirez misplayed a soft linerhit right at him by Billy Butler, and Axelrod fielding a little chopper and rushed the throw past first baseman Adam Dunn for a two-base error.
The Sox (12-16) are 2-2 on a road trip that started with two wins and a loss against the Rangers in Texas. The Royals improved to 16-10 by defeating the Sox for the 12th time in thelr last 16 games at Kauffman.