John Danks is expected to make his first start of the season Friday against the Miami Marlins at U.S. Cellular Field.
The Sox will wait until after Wednesday night's game against the Boston Red Sox to make it official.
Danks, who had shoulder surgery in August, hasn't pitched since last May. His last game was at Wrigley Field against the Cubs. His second start would line up Wednesday at Wrigley Field.
"It's been a long process,'' Danks said Tuesday after throwing a side session in the bullpen under watchful eyes of manager Robin Ventura, pitching coach Don Cooper and bullpen coach Bobby Thigpen. "Hopefully it ends this weekend.
"It's been long, lost season and it's hard to watch. I'm getting excited about getting back out there.''
Danks made four minor-league rehab starts. The results were mixed.
"I feel like I'm close to getting where my stuff was before I got hurt so, stuff-wise there won't be too much of a dropoff,'' he said. "My biggest thing is throwing the ball where I want to and making it do what I want it to do. So the stuff is going to be fine.''
Danks signed a $65 million, five-year contract before the 2012 season.
"I know it's expected of me to do more and I accept it,'' he said.