BALTIMORE -- Taylor Teagarden and Adam Jones homered in a four-run fourth inning against rookie left-hander Jose Quintana, lefty Zach Britton kept the Sox bats in check, and the Orioles defeated the Sox 5-3 on Thursday afternoon.
Quintana allowed five runs on seven hits over 3 1/3 innings. The Sox bullpen held the Orioles to one hit after Quintana left, and the Sox made it interesting for a moment in the ninth after Alexei Ramirez drove in two runs with a single against Orioles closer Jim Johnson.
Johnson struck out Gordon Beckham to end the game.
Ramirez has 62 RBI, two more than Sox cleanup man Paul Konerko.
The Orioles won three of four games against the Sox, who open a three-game series against the Detrot Tigers in Detroit on Friday night.
Britton improved to 4-1.