BOSTON -- White Sox manager Robin Ventura confirmed that left-hander Pedro Hernandez will start Wednesday night's game against the Red Sox at Fenway Park.

Hernandez, acquired during the off-season along with Simon Castro in the trade for All-Star outfielder Carlos Quentin, will make be called up from AAA Charlotte to make his major-league debut.

Hernandez allowed five runs on 12 hits over 12 innings at Charlotte after going 7-2 with a 2.75 ERA at AA Birmingham.

The Sox will make a roster move before Wednesday's game. Hernandez will be the 10th rookie pitcher and 12th rookie overall on the 25-man roster.

"He and [Jose Quintana] were in the same role [during spring training],'' manager Robin Ventura said. "You kind of hope to catch lightning twice, really.''

Quintana will pitch Thursday in the finale of the four-game series. Jake Peavy (Friday), Chris Sale (Saturday) and Dylan Axelrod (Sunday) are lined up to face the Tigers in Detroit this weekend.