OAKLAND -- Paul Konerko hit his 400th career home run Wednesday, and he picked a dramatic time to achieve the feat.

Leading off the ninth inning against Oakland A's closer Grant Balfour, Konerko hit the first pitch over the 367-foot sign in left field to put the White Sox in a 2-2 tie.

It was Konerko's fourth home run of the season.

Chris Sale pitched eight strong innings for the Sox, giving way to Addison Reed in the bottom of the ninth.

Konerko was tied with Andres Galarraga and Al Kaline on the all-time list at 399. He has hit 393 homers in a Sox uniform.

Konerko's milestone home runs: No. 1, June 6, 1998 at Seattle; No. 100, June 22, 2002 at Atlanta; Aug. 13, 2005 at Boston; No. 300, April 13, 2009 at Detroit.