Nielsen Media Research says that 16.4 million people watched the two-hour finale of "ER." That's the most-watched swan song for a television drama since "Murder She Wrote" in 1996.

Can you tell which season of "ER" this cast photo is from? (File)

As "ER," Chicago's favorite hospital drama, wraps up this week -- 8 p.m. Thursday (after a one-hour retrospective) on WMAQ-Channel 5 -- indulge in our series all about the show, it history and its Chicago roots. All those links are below, not to mention the other posts here with videos.

What are your favorite memories about the show? Favorite characters, scenes, seasons? And what on earth will you do without it after Thursday night? Comments below ...

Why is "ER" set in Chicago? Thank "St. Elsewhere"

"ER" gave real docs a taste of their own medicine

I owe half my life to "ER," fan says

"ER" staff's relatives steal the show

Where exactly is County General? Nobody knows

U of C copters deliver realism to "ER"

Clooney or not, "ER" is a prankster's paradise

The episodes few fans can forget

The kiss that lingered

The show's almost as realistic as spending a night in the ER

A fever chart for "ER" originals' careers

"ER" viewers saw Clooney as Dr. Feelgood

Future stars cut their teeth practicing in "ER"

"ER" outlasted a slicker rival: "Chicago Hope"

"ER's" past, present and suture

Season summaries:
Season 15
Season 14
Season 13
Season 12
Season 11
Season 10
Season 9
Season 8
Season 7
Season 6
Season 5
Season 4
Season 3
Season 2
Season 1

How much will you miss "ER"?

Here's a scene from "ER's" 13th season, an episode called "The Honeymoon Is Over," via YouTube ...

... and now watch a local fan's video of that same scene being filmed on the streets of Chicago, via YouTube:

Well, this is the Windy City, after all. And in just over one minute, a simple change of wind wrecked a medical helicopter on "ER" and caused all kinds of mayhem ...

The cast of "ER" is known for its on-set pranks. George Clooney was a real devil at this, but others soon got in on the act.

Here's a brief explanation of once such gotcha ...

There's a great video here, too, about the pranks -- booby traps, clowning around, greasy balls and more.

You can see Clooney's pranks galore in the gag reel posted here, too.

ER chief Kerry Weaver (Laura Innes) was the longest-running lesbian character on TV. Here are the scenes in "ER" that helped make history ...

The kiss that started it all -- with staff psychiatrist Kim Legaspi (Elizabeth Mitchell, who now plays Juliet on "Lost")

More after the jump ...

Here's another highlights reel, complete with music.

Season 5 ... oh yeah, Noah Wylie's beard ...

Season four was George Clooney's last full season on "ER." In this blooper reel, you can see what a cut-up prankster he was to work with ...

The season began with Dr. Carter entering the surgical internship (i.e., hell) and manny of our other favorite moments in this highlight reel ...

A highlight reel from season 2 ...

A scene from the 'ER' pilot ...

More after the jump ...