Former "ER" star Anthony Edwards will appear in one episode during the long-running show's final season this year. And, in his words, he thinks fellow former series luminary George Clooney "would be a fool not to" join him.

What would Dr. Greene and Dr. Ross have to say to each other after all these years? Especially since Edwards' Greene left the show by, uh, dying.

Watch Edwards discuss the possibility after the jump...