David "Honeyboy" Edwards
9 p.m. at Hideout; $12
"Living legend" can be an overused term, but it's hard to think of any other way to describe 95-year-old "Honeyboy" Edwards. The singer/guitarist has been playing the Delta blues since the Great Depression and is one of the few people alive who can talk about the great Robert Johnson from personal experience. He's been recording since World War II and continues to tour regularly, but this will be his last scheduled stop in his hometown till next February.

Rundown Alzheimer’s
7 p.m. at U.S. Cellular Field; $15-$70
The Alzheimer’s Association has raised nearly $10,000 for this event, which features a two-mile run inside the Cell, followed by a concert by Brad Cole. There will also be raffles and prizes throughout the night.

Orgone
8 p.m. at Lincoln Hall; $10
Orgone’s distinct blend of hard-edged funk, disco and Brazilian- and African-inspired grooves have impressed some of the industry's heaviest hitters, resulting in a wide array of collaborations ranging from hip-hop giants De La Soul and Pharcyde to R&B sensation Anthony Hamilton and New Orleans funk legend Eddie Bo. For their show at Lincoln Hall they will be celebrating their newest album, Cali Fever, and since this is one of only three stops in the Midwest, expect them to be at their best. The Right Now, Nootka Sound and The Dirty Diamonds DJs open.