Oscar winner Charlize Theron is teaming up with Oprah's Angel Network to educate children in her home country of South Africa about HIV and to provide treatment to kids in schools.
The two announced the endeavor -- called Mpilonhle which means "a good life" -- on Monday's show.
"Medical staff told me many students here have lost one or both parents to AIDS," Charlize says. "The mobile clinic is one of the few places offering help, guidance and a safe place to talk."
Theron Charlize is a former model known for her role in the film "Monster."