Prognosis: "He is recovering from a knee injury and is expected to return this weekend."
Though Pittsburgh is hopeful Parker can return this week- he hasn't taken a handoff since a dubious 13-carry, 20-yard performance against the Eagles week three- it's not a slam dunk. Parker may have reinjured his knee in practice this week. He was limited in practice on Thursday after participating at full speed on Wednesday. Even if Parker does go, he won't be a great start this week against a tough Giants defense.
Prognosis: "He is recovering from a slightly torn hamstring."
He hasn't been ruled out yet, but Addai is likely to miss his second straight game this week against the undefeated Titans. Expect Dominic Rhodes to again get the bulk of the carries in his place. Don't expect another two score from Rhodes this week again. The Titans run defense is ferocious.
Prognosis: "He is dealing with a lower leg injury"
Chambers will be a game-time decision this week in New Orleans. He's missed the last two games, but did score the last game he played against the Dolphins in week five. The Saints pass defense is nothing special, so this game has shootout written all over it. If Chambers plays, start him.