NU (20-1) will face Maryland, the alma mater of Wildcats coach Kelly Amonte Hiller in Sunday's title game. Maryland beat Syracuse 14-5 in its semifinal.
The game was tied at 4 at halftime before the the Cats took control.
Sophomore goalie Brianne LoManto was also superb for NU, which lost to the Tar Heels 18-16 in Evanston on April 18.
The largest crowd to ever attend a women's lacrosse game in the United States packed into Johnny Unitas Stadium in Towson, Maryland