The expected starting lineup changes for the Bears are official, or as official as they can be until the defense takes the field.
Nick Roach will start at strong-side linebacker in place of Pisa Tinoisamoa, who is week-to-week with a sprained right knee.
Danieal Manning will make his 29th career start at free safety, taking over for Kevin Payne at the position.
Zack Bowman will make his first career start at right cornerback.
Hunter Hillenmeyer is stepping in for Brian Urlacher at middle linebacker.
For Pittsburgh, inside linebacker Lawrence Timmons will start. He missed the opener with a high ankle sprain, and reportedly tweaked it during the week in practice.